LM1905
Avanti
17:0-20:4 PI(3,5)P2
Avanti Research™ - A Croda Brand LM1905, powder
동의어(들):
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt)
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C46H92N3O19P3
CAS Number:
Molecular Weight:
1084.15
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
양식
powder
제조업체/상표
Avanti Research™ - A Croda Brand LM1905
포장
1 ea of 1 × (with stopper and crimp cap (LM1905-1EA))
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
InChI key
HTHVVOQZWMVYGD-PTCSKDOGSA-N
일반 설명
Phosphorylated phosphatidylinositol (PIP) lipids are low-abundance lipids of which phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is rare. PI(3,5)P2 is localized to many cellular compartments.
생화학적/생리학적 작용
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is a signaling molecule involved in various cellular pathways. It is significant for cellular homeostasis and adaptation. Insufficiency of PI(3,5)P2 is associated with nervous system disorders.
포장
2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1905-1EA)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
가장 최신 버전 중 하나를 선택하세요:
Amber J McCartney et al.
BioEssays : news and reviews in molecular, cellular and developmental biology, 36(1), 52-64 (2013-12-11)
Recent studies of the low abundant signaling lipid, phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2 ), reveal an intriguingly diverse list of downstream pathways, the intertwined relationship between PI(3,5)P2 and PI5P, as well as links to neurodegenerative diseases. Derived from the structural lipid phosphatidylinositol
Yvonne Lindsay et al.
Journal of cell science, 119(Pt 24), 5160-5168 (2006-12-13)
Phosphatidylinositol (3,4,5) trisphosphate [PtdIns(3,4,5)P3] is a lipid second messenger, produced by Type I phosphoinositide 3-kinases (PI 3-kinases), which mediates intracellular responses to many growth factors. Although PI 3-kinases are implicated in events at both the plasma membrane and intracellular sites
Natsuko Jin et al.
Biochemical Society transactions, 44(1), 177-184 (2016-02-11)
Phosphorylated phosphatidylinositol lipids are crucial for most eukaryotes and have diverse cellular functions. The low-abundance signalling lipid phosphatidylinositol 3,5-bisphosphate [PI(3,5)P2] is critical for cellular homoeostasis and adaptation to stimuli. A large complex of proteins that includes the lipid kinase Fab1-PIKfyve
Yimei Huang et al.
Frontiers in microbiology, 10, 1016-1016 (2019-06-06)
Fungal glucosylceramide plays important role in cell division, hyphal formation and growth, spore germination and the modulation of virulence and has recently been considered as target for small molecule inhibitors. In this study, we characterized CgGCS, a protein encoding a
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