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P-075

Supelco

Primidone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C12H14N2O2
CAS Number:
125-33-7
Molecular Weight:
218.25
EC Number:
200-659-6
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

certified reference material

Quality Level

300

형태

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

농도

1.0 mg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

single component solution

저장 온도

−20°C

SMILES string

CCC1(C(=O)NCNC1=O)c2ccccc2

InChI

1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)

InChI key

DQMZLTXERSFNPB-UHFFFAOYSA-N

유전자 정보

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

일반 설명

Primidone, marketed as the barbiturate Mysoline®, Prysoline, or Liskantin®, is an anticonvulsant used in the treatment of partial and generalized seizures. This Certified Spiking Solution® is suitable for use in LC/MS or GC/MS applications in clinical toxicology or therapeutic drug monitoring to ensure patients remain within the drug′s therapeutic range.

애플리케이션


  • LC-MS/MS-Based Quantification of 9 Antiepileptic Drugs From a Dried Sample Spot Device.: This study utilizes PrimiDonesolution as a reagent in the development of a high-throughput method for quantifying antiepileptic drugs. PrimiDone is critical for accurate measurements in biochemical and pharmacological research, especially in epilepsy studies (DUrso et al., 2019).

  • Application of packed column supercritical fluid chromatography to the simultaneous determination of seven anticonvulsant drugs.: The research demonstrates the use of PrimiDonesolution in supercritical fluid chromatography to simultaneously determine multiple anticonvulsants, highlighting its importance as a stable reagent for laboratory use and anticonvulsant research (Bhoir et al., 1999).

  • The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. I. The influence of administration vehicles.: This paper discusses the use of PrimiDonesolution as a vehicle in laboratory evaluations of anticonvulsant drugs, emphasizing its stability and reliability for pharmacological experimentation and neurological disorder research (Loscher et al., 1990).

  • Simple GLC analysis of anticonvulsant drugs in commercial dosage forms.: This study utilizes PrimiDonesolution in gas-liquid chromatography to analyze commercial anticonvulsant drugs, underlining its role as a high-purity reagent for biochemical studies and anticonvulsant research (Watson et al., 1978).

  • Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.: PrimiDonesolution is used in a rapid micromethod for serum analysis of anticonvulsants, demonstrating its utility as a PrimiDone reagent for anticonvulsant research and in vitro biochemical studies (Soldin and Hill, 1976).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Liskantin is a registered trademark of Desitin Arzneimittel GmbH
Mysoline is a registered trademark of Valeant Pharmaceuticals North America LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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P-004

Phenobarbital-D5 (side chain) solution, (deuterium label on side chain), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-017

Phenobarbital-D5 (side chain) solution, (deuterium label on side chain), 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-018

Phenobarbital-D5 (ring) solution, (deuterium label on ring), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-019

Phenobarbital-D5 (ring) solution, (deuterium label on ring), 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-138

Primidone-D5 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

픽토그램

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

신호어

Danger

유해 및 위험 성명서

H225,H301 + H311 + H331,H370

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Günther Deuschl et al.
The Lancet. Neurology, 10(2), 148-161 (2011-01-25)
Essential tremor is a common movement disorder. Tremor severity and handicap vary widely, but most patients with essential tremor do not receive a diagnosis and hence are never treated. Furthermore, many patients abandon treatment because of side-effects or poor efficacy.
Nancy L Diaz et al.
Parkinsonism & related disorders, 16(9), 604-607 (2010-08-10)
Although small treatment trials have examined the efficacy of front-line medications in tremor reduction in essential tremor (ET), an overall survey of pharmacological management has not been undertaken in a large sample of ET cases. To conduct a survey of
B Rezaei et al.
Talanta, 79(3), 669-675 (2009-07-07)
Application of electrospray ionization ion mobility spectrometry (ESI-IMS) as the detection technique for separation method based on molecular imprinted polymer (MIP) was investigated and evaluated. The method is exhaustively validated, including sensitivity, selectivity, recovery, reproducibility, and column capacity. The linear
Feng Chen et al.
Environmental pollution (Barking, Essex : 1987), 159(6), 1490-1498 (2011-04-12)
This study investigated the occurrence of 43 emerging contaminants including 9 endocrine-disrupting chemicals and 34 pharmaceuticals in three sites in Hebei Province, north China. Each site has a wastewater irrigated plot and a separate groundwater irrigated plot for comparison purpose.
Christopher G Favilla et al.
Parkinsonism & related disorders, 19(2), 171-175 (2012-10-16)
Many essential tremor patients continue to require tremor suppressing medications following deep brain stimulation. The true incidence of medication usage in the years following surgery remains unclear, and the use of medications has not been included in the post-operative analyses
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