1.02497

NMP

for headspace gas chromatography SupraSolv^®

• 동의어(들): 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• CAS Number: 872-50-4
• Molecular Weight: 99.13
• MDL number: MFCD00003193
• UNSPSC 코드: 41116105
• EC 인덱스 번호: 212-828-1
• NACRES: NA.03

속성

• product name: 1-Methyl-2-pyrrolidone, for headspace gas chromatography SupraSolv^®
• vapor pressure: 0.32 hPa ( 20 °C)
• Quality Level: 100
• 제품 라인: SupraSolv^®
• 분석: ≥99.8% (GC)
• 형태: liquid
• autoignition temp.: 245 °C
• 효능: 3598 mg/kg LD₅₀, oral (Rat); 8000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.3-9.5 % (v/v)
• 기술: GC-HS: suitable
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• bp: 202 °C/1013 hPa
• mp: -24 °C
• 전이 온도: flash point 91 °C
• solubility: 1000 g/L
• density: 1.03 g/cm³ at 20 °C
• 저장 온도: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI key: SECXISVLQFMRJM-UHFFFAOYSA-N

설명

일반 설명

SupraSolv^® high-purity solvents are specially designed for headspace-gas chromatography (HS-GC) for the analysis of residual solvents (RS) in active pharmaceutical ingredients, excipients and drug products according to Ph. Eur and USP. The concentrations of RS for high purity solvents are specified following ICH (International Council for Harmonizaton of Technical Requirements for Registration of Pharmaceuticals for Human Use) Guideline Q3C “Impurities: Guideline for Residual Solvents”.

애플리케이션

Intended for sensitive detection of analytes of ICH classes 1, 2 and 3 in residue and environmental analysis:

Every residual solvent of class 1 acc. ICH ≤ 1 μg/g
Every residual solvent of class 2 acc. ICH ≤ 10 μg/g
Every residual solvent of class 3 acc. ICH ≤ 50 μg/g

기타 정보

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

법적 정보

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H315 - H319 - H335 - H360D
• 예방조치 성명서: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point (°F): 195.8 °F - Pensky-Martens closed cup
• Flash Point (°C): 91 °C - Pensky-Martens closed cup