204897

Complement C4b, Human

Complement C4b, Human, is a native, 193 kDa glycoprotein composed of the modified C4 α-chain (α′) and intact β- and γ-chains complement component.

• UNSPSC 코드: 12352202
• NACRES: NA.25

속성

• Quality Level: 100
• 분석: ≥95% (SDS-PAGE)
• 형태: liquid
• 미포함: preservative
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; avoid repeated freeze/thaw cycles
• 불순물: IgG, IgA, IgM, Factor B, Factor H, C3, ceruloplasmin, or albumin, trace
• 배송 상태: wet ice
• 저장 온도: −70°C

설명

생화학적/생리학적 작용

Complement C4b fragment is formed by the cleavage of the C4 α-chain by activated C1 enzyme. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Target surface-bound C4b acts as an important non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b, C2a). This surface-bound C4b also exhibits opsonic and immune adherence activities which are dependent on the CR1 (CD35) complement receptor found on many inflammatory cells.

ComplementC4b fragment is formed by the cleavage of the C4 α-chain by activated C1enzyme. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Target surface-bound C4b acts as an important non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b, C2a). This surface-bound C4b also exhibits opsonic and immune adherence activities which are dependent on the CR1 (CD35) complement receptor found on many inflammatory cells.

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable