3741

Hemin Chloride

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

• 동의어(들): Hemin Chloride
• CAS Number: 16009-13-5
• MDL number: MFCD00010726
• UNSPSC 코드: 12352202
• NACRES: NA.21

속성

• Quality Level: 100
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: dark purple
• solubility: 0.1-1.0 M NaOH: soluble; 1 N NH₄OH: soluble
• 배송 상태: ambient
• 저장 온도: 15-25°C
• InChI: 1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2
• InChI key: GGIDWJQWCUJYRY-UHFFFAOYSA-L

설명

일반 설명

Iron containing compound of porcine origin that can induce H₂O₂-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions. Induces heme-oxygenase-1 activity and reduces renal injury induced by mercuric compounds.

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

애플리케이션

• Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: Discusses the therapeutic potentials of hemin chloride in neurological disorders, highlighting its role in mitigating cytotoxic effects associated with genetic mutations, significant for advancing neurodegenerative disease treatments (Hirayanagi K et al., 2021).


• Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: Demonstrates the application of hemin chloride in enhancing signal detection in spectroscopic analysis, important for improving analytical methods in environmental and food sciences (López-Castaños KA et al., 2020).

경고

Toxicity: Standard Handling (A)

재구성

Unstable in solution; reconstitute just prior to use.

분석 메모

homogeneous by TLC

기타 정보

Yonega, R., et al. 2000. Toxicol. Lett.116, 223.
Funanage, V.L., et al. 1989. J. Cell. Physiol.141, 591.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable