M9429

Menadione

meets USP testing specifications

• 동의어(들): 2-Methyl-1,4-naphthoquinone, Vitamin K₃
• 실험식(Hill 표기법): C₁₁H₈O₂
• CAS Number: 58-27-5
• Molecular Weight: 172.18
• Beilstein: 1908453
• EC Number: 200-372-6
• MDL number: MFCD00001681
• UNSPSC 코드: 12352205
• PubChem Substance ID: 24897335
• NACRES: NA.21

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• Agency: USP/NF; meets USP testing specifications
• 분석: 98.5-101.0% dry basis
• 형태: solid
• mp: 105-107 °C (lit.)
• 응용 분야: pharmaceutical (small molecule)
• SMILES string: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• InChI key: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• 유전자 정보: human ... NQO1(1728)

설명

일반 설명

Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets.

애플리케이션

Menadione has been used:

• to treat HL-60 cells as positive control for apoptosis for flow cytometry
• as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization
• to treat HaCaT cell line, for quantifying total and oxidised glutathione

생화학적/생리학적 작용

Menadione is an oxidative stress inducer.

안전성 정보

• 픽토그램: GHS07,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H317,H319,H335,H410
• 예방조치 성명서: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves