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Merck
모든 사진(4)

주요 문서

V3501

Sigma-Aldrich

Vitamin K1

viscous liquid

동의어(들):

2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K1(20)

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About This Item

실험식(Hill 표기법):
C31H46O2
CAS Number:
Molecular Weight:
450.70
Beilstein:
2568816
EC Number:
MDL number:
UNSPSC 코드:
12352205
eCl@ss:
34058015
PubChem Substance ID:
NACRES:
NA.28

생물학적 소스

synthetic (organic
inorganic)

Quality Level

형태

viscous liquid

색상

, Yellow to Very Dark Yellow to Very Dark Orange

refractive index

n20/D 1.527 (lit.)

mp

−20 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

저장 온도

2-8°C

SMILES string

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

InChI key

MBWXNTAXLNYFJB-NKFFZRIASA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Vitamin K1/Phylloquinone is a prenylated naphthoquinone. It is produced by plants, green algae and some species of cyanobacteria.

애플리케이션

Vitamin K1 has been used in the preparation of culture media.

생화학적/생리학적 작용

Vitamin K1 (Phylloquinone) is a lipid soluble polycyclic aromatic ketone used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor. Vitamin K1 is essential for blood coagulation, bone and vascular metabolism. Phylloquinone from green leafy vegetables and vegetable oil is the most important dietary source of vitamin K for humans.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Bacteroides disiens sp. nov. and Bacteroides bivius sp. nov. from human clinical infections
Holdeman L V and Johnson J L
International Journal of Systematic and Evolutionary Microbiology (1977)
Phylloquinone (vitamin K1): occurrence, biosynthesis and functions
Basset J G, et al.
Mini-Reviews in Medicinal Chemistry (2017)
Ellen M Apalset et al.
Bone, 49(5), 990-995 (2011-08-16)
Evidence of the effect of vitamin K on bone health is conflicting. The aim was to investigate the association between intake of vitamins K1 and K2 and subsequent risk of hip fracture in a general population sample, as well as
Edward P A Gebuis et al.
Haematologica, 96(4), 583-589 (2011-01-05)
Poor anticoagulant stability in patients using vitamin K antagonists is a risk factor for both bleeding and thrombosis. In previous studies supplementation with low dose vitamin K(1) was shown to improve the stability of anticoagulant control. We set up a
Beverly Murray et al.
The Journal of antimicrobial chemotherapy, 75(8), 2149-2155 (2020-04-15)
Ibezapolstat (ACX-362E) is the first DNA polymerase IIIC inhibitor undergoing clinical development for the oral treatment of Clostridioides difficile infection (CDI). In this study, the in vitro activity of ibezapolstat was evaluated against a panel of 104 isolates of C.

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