추천 제품
Grade
analytical standard
Quality Level
분석
≥90%
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
forensics and toxicology
pharmaceutical (small molecule)
형식
neat
저장 온도
2-8°C
SMILES string
[Na+].COc1cc(c(cc1-n2nc(n[n+]2-c3cc(c(cc3OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc4ccccc4)S([O-])(=O)=O)[N+]([O-])=O
InChI
1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
InChI key
JACYMBNQPPWQML-UHFFFAOYSA-M
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애플리케이션
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Useful in AIDS and cancer testing.
XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines. The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.
원리
In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Self-react. C
보충제 위험성
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Parsons, J.L., et al.
Journal of Heterocyclic Chemistry, 25, 911-911 (1988)
Wander José da Silva et al.
Brazilian dental journal, 19(4), 364-369 (2009-01-31)
2, 3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino) carbonyl]-2H-tetrazolium hydroxide (XTT) reduction assay has been used to study Candida biofilm formation. However, considering that the XTT reduction assay is dependent on cell activity, its use for evaluating mature biofilms may lead to inaccuracies since biofilm
D A Scudiero et al.
Cancer research, 48(17), 4827-4833 (1988-09-01)
We have previously described the application of an automated microculture tetrazolium assay (MTA) involving dimethyl sulfoxide solubilization of cellular-generated 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)-formazan to the in vitro assessment of drug effects on cell growth (M.C. Alley et al., Proc. Am. Assoc.
Cristina Sánchez-Quesada et al.
Evidence-based complementary and alternative medicine : eCAM, 2018, 9473094-9473094 (2018-10-27)
Anti-inflammatory effects of virgin olive oil (VOO) have been described recently, along with its wound healing effect. One of the main minor compounds found in VOO is squalene (SQ), which also possesses preventive effects against skin damage and anti-inflammatory properties.
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