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Merck
모든 사진(1)

Key Documents

552233

Sigma-Aldrich

QX-314

≥99% (HPLC), lyophilized solid, voltage-sensitive Na+ conductance blocker, Calbiochem®

동의어(들):

QX-314

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C16H27BrN2O
CAS Number:
21306-56-9
Molecular Weight:
343.30
MDL number:
MFCD00083182
UNSPSC 코드:
12352200
NACRES:
NA.77

product name

QX-314, A quaternary lidocaine derivative, permanently charged, and lipophobic.

Quality Level

100

분석

≥99%

형태

lyophilized solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
protect from light

solubility

water: 3 mg/mL

배송 상태

ambient

저장 온도

10-30°C

InChI

1S/C16H26N2O/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5/h9-11H,6-8,12H2,1-5H3/p+1

InChI key

PYEBKOFMWAMBFV-UHFFFAOYSA-O

일반 설명

A quaternary lidocaine derivative, permanently charged, and lipophobic. A powerful blocker of voltage-sensitive Na+ conductance when applied intracellularly. Suppresses the generation of Na+-dependent spikes from inside the cell membrane, without affecting Ca2+ currents or glutamate-activated currents.

생화학적/생리학적 작용

Cell permeable: no
Primary Target
A powerful blocker of voltage-sensitive Na+ conductance
Product does not compete with ATP.
Reversible: no
fully active in neurophysiological testing

경고

Toxicity: Irritant (B)

기타 정보

Mooney, R. 1992. J. Neurosci.12, 2464.
Regehr, W.G. and Tank, D.W. 1992. J. Neurosci.12, 4202.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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