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Merck
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Key Documents

ABS30

Sigma-Aldrich

Anti-Sulfenic Acid Modified Cysteine (2-Thiodimedone-Specific Ig) Antibody

serum, from rabbit

동의어(들):

Sulfenic Acid Modified Cysteine (2-Thiodimedone-Specific Ig)

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human, mouse, rat

종 반응성(상동성에 의해 예측)

all

기술

western blot: suitable

동형

IgG

배송 상태

wet ice

타겟 번역 후 변형

unmodified

일반 설명

Protein sulfenic acid formation is a reversible post-translational modification that may be used to monitor protein oxidation on reactive cysteines within target proteins. This can be detected with protein sulfenic acid derivatised with dimedone.

특이성

This anitbody recognizes sulfenic acid modified proteins. Pan modification against all species.

면역원

Linear peptide corresponding to sulfenic acid modified proteins.

애플리케이션

Anti-Sulfenic Acid Modified Cysteine (2-Thiodimedone-Specific Ig) Antibody detects level of Sulfenic Acid Modified Cysteine & has been published & validated for use in WB.
Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF. (Seo, YH, et al. (2009). PNAS. 106(38): 16163-16168.)

품질

Evaluated by Western Blot in rat ventricular myocyte lysate.

Western Blot Analysis: 01:1,000 dilution of this antibody detected sulfenic acid modified proteins on 10 µg of rat ventricular myocyte lysate.

표적 설명

Pan antibody smear is expected.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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Molecular cell, 48(1), 39-51 (2012-09-18)
Endoplasmic reticulum (ER) thiol oxidases initiate a disulfide relay to oxidatively fold secreted proteins. We found that combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1α, ERO1β, and PRDX4 compromised the extracellular matrix in mice and interfered with
Phillip A Wages
Current protocols in toxicology, 71, 17-17 (2017-02-02)
Protein sulfenylation is a post-translational modification that is linked to many cell signaling networks and specific protein functions, thus the detection of any sulfenylated protein after a toxicological exposure is of importance. Specifically, the detection of protein sulfenylation can provide
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