추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
mouse, rat
기술
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
mouse ... Sh3Gl2(20404)
일반 설명
A member of the Endophilin family, Endophilin A1 is a protein containing SH3 domains, and has been implicated in the trafficking of clathrin-mediated synaptic vesicle endocytosis within the membrane. It was originally characterized as a presynaptically enriched protein that binds to endocytic proteins polyphosphoinositide synaptojanin and dynamin. Endophilin A1 has been implicated in endocytic vesicle budding when its function in cell-free systems and in living synapses has been disturbed. Along with the SH3 domain, Endophilin A1 contains a BAR domain in the N-terminal region, that has been found to induce and bind membrane curvature. This protein’s expression is localized to the brain, most specifically in the frontal cortex. Markedly high expression is observed in fetal cerebellum.
특이성
Human (94% sequence homology).
The antibody recognizes Endophilin-A1.
면역원
KLH-conjugated linear peptide corresponding to mouse Endophilin-A1.
애플리케이션
This Anti-Endophilin-A1 Antibody is validated for use in WB for the detection of Endophilin-A1.
Western Blot Analysis: 1:500 dilution from a previous lot detected Endophilin-A1 in 10 µg of rat brain and mouse brain membrane tissue lysates.
품질
Evaluated by Western Blot in mouse brain tissue lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected Endophilin-A1 in 10 µg of mouse brain tissue lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected Endophilin-A1 in 10 µg of mouse brain tissue lysate.
표적 설명
~ 42 kDa
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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