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Merck
모든 사진(1)

주요 문서

MAB364

Sigma-Aldrich

Anti-MAP2 Antibody

CHEMICON®, mouse monoclonal, HM-2

동의어(들):

Anti-MAP-2, Anti-MAP2A, Anti-MAP2B, Anti-MAP2C

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

product name

Anti-MAP2A, 2B, 2C Antibody, clone HM-2, ascites fluid, clone HM-2, Chemicon®

생물학적 소스

mouse

Quality Level

항체 형태

ascites fluid

항체 생산 유형

primary antibodies

클론

HM-2, monoclonal

종 반응성

bovine, human, quail, rat, chicken, mouse

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable
western blot: suitable

동형

IgG1

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... MAP2(4133)

특이성

Shows selective staining of dendritic trees throughout the brain in immunohistochemical staining of brain tissue. In perkinje neurons, staining is restricted to the dendrites distal to the initial dendrite segment. No staining of cell body in mature Perkinje cells but strong staining of cell bodies of developing Perkinje cells from neonatal rats. No detectable staining of axons or non-neuronal cells. Reacts specifically with all forms of MAP2 (MAP2a ~280 kDa, MAP2b ~280 kDa and MAP2c ~70 kDa) as determined by immunoblot. No cross-reactivity observed to other MAPs or tubulin.

면역원

Rat brain microtubule-associated protein.

애플리케이션

Anti-MAP2A Antibody, 2B, 2C, clone HM-2 detects level of MAP2A & has been published & validated for use in WB, IH.
Immunoblotting at 1:500 using fresh rat brain extract or enriched microtubule protein preparation.

Immunohistochemistry: 1:50 to 1:1000

Optimal working dilution must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

물리적 형태

Ascites fluid. Liquid with 15 mM sodium azide.

저장 및 안정성

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

T Sorimachi et al.
Neurologia medico-chirurgica, 37(3), 236-242 (1997-03-01)
The protective effect of prior ischemia on focal cerebral infarction produced by permanent middle cerebral artery (MCA) occlusion was studied in a gerbil model. Forebrain ischemia for 2 and 5 minutes at an interval of 48 hours was used as
Jie Gao et al.
The Journal of pharmacology and experimental therapeutics, 356(3), 645-655 (2016-01-01)
The extensive use of organophosphates (OPs) is an ongoing environmental health concern due to multiple reports of OP-related neurologic abnormalities. The mechanism of the acute toxicity of OPs has been attributed to inhibition of acetylcholinesterase (AChE), but there is growing
Lauri M Louhivuori et al.
Stem cells and development, 24(6), 701-713 (2014-10-28)
The guidance of developing neurons to the right position in the central nervous system is of central importance in brain development. Canonical transient receptor potential (TRPC) channels are thought to mediate turning responses of growth cones to guidance cues through
Kentaro Takakura et al.
Heliyon, 3(11), e00462-e00462 (2017-12-22)
The genus Cordyceps and its specific ingredient, cordycepin, have attracted much attention for multiple health benefits and expectations for lifespan extension. We analyzed whether Cordyceps militaris (CM), which contains large amounts of cordycepin, can extend the survival of Dahl salt-sensitive
Lauri M Louhivuori et al.
Glia, 66(1), 94-107 (2017-09-10)
Radial glial cells play an essential role through their function as guides for neuronal migration during development. Disruption of metabotropic glutamate receptor 5 (mGluR5) function retards the growth of radial glial processes in vitro. Neuregulins (NRG) are activated by proteolytic

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