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Merck
모든 사진(1)

주요 문서

10171832001

Roche

Aldehyde Dehydrogenase

from yeast

동의어(들):

Aldehyde dehydrogenase

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About This Item

효소 위원회 번호:
UNSPSC 코드:
12352204

생물학적 소스

yeast

Quality Level

형태

lyophilized

특이 활성도

~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)

포장

pkg of 250 U

제조업체/상표

Roche

최적 pH

8.75

관련 질환(들)

cancer

저장 온도

2-8°C

일반 설명

Aldehyde dehydrogenase (ALDH) is a soluble enzyme and its activity depends on potassium ions and cysteine. The family of ALDH comprises of 19 genes in human. ALDH gene is expressed in the nucleus, cytosol, mitochondria and endoplasmic reticulum of the cell. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems.

애플리케이션

Aldehyde Dehydrogenase has been used to evaluate fiber-optic biosensors for measurement of acetaldehyde (AcH) in liquid phase (AcH biosensor).

생화학적/생리학적 작용

Aldehyde dehydrogenase (ALDH) regulates the non-P450 aldehyde reduction enzyme system. It protects the cell from the effects of toxic aldehydes. Mutations in this gene are associated with Sjogren Larsson syndrome, Larsson syndrome, type II hyperprolinemia and cancer. ALDH takes part in the oxidation of aldehydes to acids. ALDH-2 lowers cardiac ischemia, which arises due to myocardial infarction or post cardiac surgery.

품질

Contaminants: <0.01% “NADH oxidase”, ADH, and LDH each

물리적 형태

Enzyme is stabilized with potassium phosphate buffer, pH approximately 6.

기타 정보

For life science research only. Not for use in diagnostic procedures.

픽토그램

Exclamation markHealth hazard

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Yeast Aldehyde Dehydrogenase II. PROPERTIES OF THE HOMOGENEOUS ENZYME PREPARATIONS
Charles R. Steinman and WILLIAM B. JAKOBY
The Journal of Biological Chemistry, 243(4), 730-734 (1965)
Kenta Iitani et al.
Sensors (Basel, Switzerland), 23(13) (2023-07-14)
The molecule 2-nonenal is renowned as the origin of unpleasant human aging-related body odor that can potentially indicate age-related metabolic changes. Most 2-nonenal measurements rely on chromatographic analytical systems, which pose challenges in terms of daily usage and the ability
Improved sensitivity of acetaldehyde biosensor by detecting ADH reverse reaction-mediated NADH fluoro-quenching for wine evaluation
Iitani K, et al.
ACS sensors, 2(7), 940-946 (2017)
Yeast aldehyde dehydrogenase.
S BLACK
Archives of biochemistry and biophysics, 34(1), 86-97 (1951-11-01)
Hui Han et al.
Alcoholism, clinical and experimental research, 43(6), 1091-1102 (2019-03-26)
We previously developed enzyme nanoparticles (ENP) of alcohol metabolism. This study was to evaluate protective effects of facilitated removal of blood alcohol and/or acetaldehyde on anti-HIV drugs and alcohol-induced liver injuries. ENP were prepared for degrading alcohol completely (ENP1) or

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