03738
5-Fluorouracil
analytical standard
동의어(들):
2,4-Dihydroxy-5-fluoropyrimidine, 5-FU, 5-Fluoro-2,4(1H,3H)-pyrimidinedione
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C4H3FN2O2
CAS Number:
Molecular Weight:
130.08
Beilstein:
127172
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
analytical standard
Quality Level
분석
≥99.0% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
불순물
≤0.5% water
mp
282-286 °C (dec.) (lit.)
응용 분야
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
형식
neat
SMILES string
FC1=CNC(=O)NC1=O
InChI
1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChI key
GHASVSINZRGABV-UHFFFAOYSA-N
유전자 정보
human ... TYMS(7298)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
5-Fluorouracil is an anti-tumor agent, widely used in the treatment of various malignancies.
애플리케이션
5-Fluorouracil may be used as an analytical standard for the determination of the analyte in hospital effluents by capillary electrophoresis, and in biological samples and environmental samples by chromatography based techniques.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
이미 열람한 고객
Susanne N Mahnik et al.
Analytical and bioanalytical chemistry, 380(1), 31-35 (2004-09-15)
Cytostatic anticancer drugs are an increasingly important issue in the environmental debate, mainly due to the lack of knowledge about the fate of these toxic substances. Over the last decades, 5-fluorouracil (5-FU) has been one of the most frequently used
A sensitive method for determination of 5-fluorouracil and 5-fluoro-2'-deoxyuridine in human plasma by high-pressure liquid chromatography.
A R Buckpitt et al.
Analytical biochemistry, 106(2), 432-437 (1980-08-01)
Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer
Carethers JM, et al.
Gastroenterology, 126(2), 394-401 (2004)
G Micoli et al.
Journal of chromatography. B, Biomedical sciences and applications, 750(1), 25-32 (2001-02-24)
5-Fluorouracil (5-FU) is one of the most widely used antineoplastic drugs. It can be therefore considered to be a model compound for the identification of exposure routes during preparation and administration of cytostatic agents, especially for nucleoside analogue drugs. In
5-fluorouracil: mechanisms of action and clinical strategies
Longley DB, et al.
Nature Reviews. Cancer, 3(5), 330-338 (2003)
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