추천 제품
Quality Level
분석
≥99.0% (N)
≥99.0%
형태
powder
품질
for spectrophotometric det. of Cu
기술
UV/Vis spectroscopy: suitable
mp
210-214 °C (lit.)
210-214 °C
SMILES string
O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2
InChI
1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
InChI key
DSRJIHMZAQEUJV-UHFFFAOYSA-N
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일반 설명
Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.
애플리케이션
Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.
기타 정보
For the spectrophotometric determination of Cu(II)
In the presence of a copper salt, this ligand catalyzes Ullmann-type C-N bond forming reactions under mild, aqueous conditions.
관련 제품
제품 번호
설명
가격
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Synthesis, 23, 3955-3962 (2006)
Cuprizone treatment induces distinct demyelination, astrocytosis, and microglia cell invasion or proliferation in the mouse cerebellum.
Cerebellum, 8 (3), 163-174 (2009)
Cortical demyelination is prominent in the murine cuprizone model and is strain-dependent.
The American Journal of Pathology, 174 (4), 1053-1061 (2008)
The protective role of nitric oxide in a neurotoxicant-induced demyelinating model.
Journal of Immunology, 168 (1), 427-433 (2002)
Analytical Chemistry, 38, 911-911 (1966)
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