71478
Nα-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide
for chiral derivatization, LiChropur™, ≥99.0%
동의어(들):
FDAA, Marfey’s reagent
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
실험식(Hill 표기법):
C9H9FN4O5
CAS Number:
Molecular Weight:
272.19
Beilstein:
6820069
MDL number:
UNSPSC 코드:
12000000
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Grade
for chiral derivatization
Quality Level
분석
≥99.0% (sum of enantiomers, TLC)
≥99.0%
형태
powder
광학 활성
[α]20/D +56±2°, c = 1% in acetone
광학 순도
enantiomeric ratio: ≥99.5:0.5 (HPLC)
품질
LiChropur™
기술
HPLC: suitable
저장 온도
2-8°C
SMILES string
C[C@H](Nc1cc(F)c(cc1[N+]([O-])=O)[N+]([O-])=O)C(N)=O
InChI
1S/C9H9FN4O5/c1-4(9(11)15)12-6-2-5(10)7(13(16)17)3-8(6)14(18)19/h2-4,12H,1H3,(H2,11,15)/t4-/m0/s1
InChI key
NEPLBHLFDJOJGP-BYPYZUCNSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Nα-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent (CDA), has high enantioselectivity but low sensitivity as compared to other CDAs. It is generally used to assign the stereochemistry of amino acids in trace amounts.
애플리케이션
FDAA was used as derivatizing reagent, in a study performed to understand unusual amino acids using reversed phase high performance liquid chromatography-electrospray ionization mass spectrometry (RPHPLC-ESI-MS).
기타 정보
Derivatization reagent for the assay of unusual chiral α-amino acid analogs
법적 정보
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Chirality determination of unusual amino acids using precolumn derivatization and liquid chromatography-electrospray ionization mass spectrometry.
Hess S
Journal of Chromatography A, 1035(2), 211-219 (2004)
B S Foster et al.
Journal of analytical toxicology, 22(4), 265-269 (1998-07-29)
An analytical method was developed for enantiomeric determination of amphetamine and methamphetamine in human urine. The enantiomers were isolated from urine by solid-phase extraction, and diastereomers were formed by derivatization with the chiral Marfey's reagent (1-fluoro-2,4-dinitrophenyl-5-l-aniline amide). The diastereomers were
Mengxuan Chen et al.
Scientific reports, 8(1), 72-72 (2018-01-10)
Marine natural products are important resources for discovering novel anticancer drugs. In this study, an extract prepared from the culture of a sea anemone-derived actinomycete Streptomyces sp. ZZ406 in soluble starch and casein-related liquid medium was found to have activity
R Bhushan et al.
Amino acids, 27(3-4), 231-247 (2004-10-27)
The present paper describes characteristics and application of Marfey's reagent (MR) including general protocols for synthesis of the reagent and diastereomers along with advantages, disadvantages and the required precautions. Applications, and comparison with other derivatizing agents, for the resolution of
D R Goodlett et al.
Journal of chromatography. A, 707(2), 233-244 (1995-07-21)
A high-performance liquid chromatography-electrospray ionization-mass spectrometric (LC-ESI-MS) method is presented that allows rapid and accurate determination of amino acid chiral purity in a peptide. Peptides are hydrolyzed in hydrochloric acid-d1/acetic acid-d4 and then converted to diastereomers by derivatization with 1-fluoro-2,4-dinitrophenyl-5-L-alanine
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.