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Merck
모든 사진(1)

주요 문서

77500

Supelco

1,10-Phenanthroline monohydrate

for the spectrophotometric determination of Fe, Pd, V, ≥99.0%

동의어(들):

o-Phenanthroline monohydrate

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About This Item

실험식(Hill 표기법):
C12H8N2 · H2O
CAS Number:
Molecular Weight:
198.22
Beilstein:
4008096
EC Number:
MDL number:
UNSPSC 코드:
12000000
PubChem Substance ID:
NACRES:
NA.21

Quality Level

분석

≥99.0% (HPLC)
≥99.0% (NT)
≥99.0%

형태

crystals

품질

for the spectrophotometric determination of Fe, Pd, V

기술

UV/Vis spectroscopy: suitable
titration: suitable

무기 잔류물

≤0.05%

mp

100-104 °C (lit.)
99-104 °C

양이온 미량물

Ca: ≤50 mg/kg
Cd: ≤20 mg/kg
Co: ≤20 mg/kg
Cr: ≤20 mg/kg
Cu: ≤20 mg/kg
Fe: ≤20 mg/kg
K: ≤100 mg/kg
Mg: ≤20 mg/kg
Mn: ≤20 mg/kg
Na: ≤100 mg/kg
Ni: ≤20 mg/kg
Pb: ≤20 mg/kg
Zn: ≤20 mg/kg

SMILES string

O.c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

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일반 설명

1,10-Phenanthroline monohydrate is a chelating agent.

애플리케이션

It has been used in preparing 0.1 % phenanthroline solution. In another study, 80μl of 1,10-Phenanthroline monohydrate was used along with nanoparticles to measure iron content using colorimetric assay.3 It may be used in the preparation of [Mn(1,10-phen)2(mal)].2H2O.
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.

생화학적/생리학적 작용

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

픽토그램

Skull and crossbonesEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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문서 라이브러리 방문

Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 15, 585-585 (1970)
Insights into the mode of action of the anti-Candida activity of 1,10-phenanthroline and its metal chelates.
McCann M
Metal-based drugs, 7(4), 185-193 (2000)
W. Sliwa
Heterocycles, 12, 1207-1207 (1979)
A newly developed Fe-doped calcium sulfide nanoparticles with magnetic property for cancer hyperthermia.
Wu, Steven Yueh-Hsiu, Ching-Li Tseng, and Feng-Huei Lin.
Journal of Nanoparticle Research, 12.4, 1173-1185 (2010)
Olivia L Lanier et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 36(1), 687-701 (2019-07-26)
Background: Magnetic nanoparticles (MNPs) generate heat when exposed to an alternating magnetic field. Consequently, MNPs are used for magnetic fluid hyperthermia (MFH) for cancer treatment, and have been shown to increase the efficacy of chemotherapy and/or radiation treatment in clinical

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