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Merck
모든 사진(4)

문서

472301

Sigma-Aldrich

Dimethyl sulfoxide

ACS reagent, ≥99.9%

동의어(들):

DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
MDL number:
UNSPSC 코드:
12191502
PubChem Substance ID:
NACRES:
NA.21

Grade

ACS reagent

Quality Level

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

분석

≥99.9%

형태

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

불순물

≤0.001 meq/g Titr. acid
≤0.1% water

증발 잔류물

≤0.01%

색상

clear colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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일반 설명

Dimethyl sulfoxide is an organosulfur, commonly used as a polar solvent that can dissolve a wide range of polar and non-polar compounds. It is also utilized as a reaction reagent in several well-known processes, including swern oxidation, 2a pfitzner-moffatt oxidation, 2b, and the corey-chaykovsky reaction.

애플리케이션

Dimethyl sulfoxide (DMSO) has been used:
  • in the preparation of ethyl 4-[18F]fluorobenzoate.
  • in the culture medium for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay.
  • as a solvent in chemical synthesis.
  • to dissolve and prepare stock solutions of small molecules, drugs, and chemical compounds for various assays and experiments.

주의사항

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

기타 정보

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

188.6 °F - closed cup

Flash Point (°C)

87 °C - closed cup


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Dimethyl sulfoxide extraction method for the liquid chromatographic analysis of microencapsulated vitamin D3
Richard P J, et al.
Journal of Agricultural and Food Chemistry, 45, 1784-1786 (1997)
The applications of dimethyl sulfoxide as reagent in organic synthesis
Xiao-Feng W, et al.
Advanced Synthesis & Catalysis, 358, 336-352 (2016)
Shuang Hou et al.
Journal of visualized experiments : JoVE, (52)(52), doi:10-doi:10 (2011-07-07)
Biomolecules, including peptides¹⁻⁹, proteins¹⁰⁻¹¹, and antibodies and their engineered fragments¹²⁻¹⁴, are gaining importance as both potential therapeutics and molecular imaging agents. Notably, when labeled with positron-emitting radioisotopes (e.g., Cu-64, Ga-68, or F-18), they can be used as probes for targeted
P Roy et al.
The FEBS journal, 277(2), 441-452 (2009-12-18)
EVI1 is a nuclear zinc finger protein essential to normal development, which participates in acute myeloid leukaemia progression and transforms Rat1 fibroblasts. In this study we show that enforced expression of Evi1 in Rat1 fibroblasts protects from paclitaxel-induced apoptosis, consistent
Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.
Omura K and Swern D.
Tetrahedron, 34(11), 1651-1660 (1978)

문서

Substances are said to be miscible in one another if they dissolve to form a uniform solution. Bookmark or download our miscibility table for common lab solvents.

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