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Merck
모든 사진(1)

주요 문서

494496

Sigma-Aldrich

NMP

biotech. grade, ≥99.7%

동의어(들):

1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

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About This Item

실험식(Hill 표기법):
C5H9NO
CAS Number:
Molecular Weight:
99.13
Beilstein:
106420
EC Number:
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.07
Grade:
biotech. grade
분석:
≥99.7%
응용 분야:
peptide synthesis
bp:
202 °C (lit.)
81-82 °C/10 mmHg (lit.)
vapor pressure:
0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

제품명

1-Methyl-2-pyrrolidinone, biotech. grade, ≥99.7%

Grade

biotech. grade

Quality Level

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

분석

≥99.7%

양식

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

불순물

≤0.005% water
≤0.01% free amines (CH3NH2)

색상

APHA: ≤20

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

solubility

acetone: miscible(lit.)
alcohol: miscible(lit.)
chloroform: miscible(lit.)
ethyl acetate: miscible(lit.)
water: miscible(lit.)

density

1.028 g/mL at 25 °C (lit.)

λ

H2O reference

UV 흡수

λ: 285 nm Amax: 1.00
λ: 300 nm Amax: 0.50
λ: 325 nm Amax: 0.10
λ: 350-400 nm Amax: 0.01

응용 분야

peptide synthesis

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

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일반 설명

N-Methyl-2-pyrrolidinone (N-methylpyrrolidone, NMP) is a polar cyclic organic solvent. A study on the impact of NMP on Saccharomyces cerevisiae revealed that it induced aneuploidy. Characteristic properties of NMP include low viscosity, excellent dissolving power and enhanced demulsifying property. It is a better alternative to phenol in selectively treating lube feedstock. The behavior of fullerene-C60 in NMP solution has been examined based on electronic absorption and photoluminescence spectral data. A solution of sodium borohydride (NaBH4) in NMP showed increased reactivity towards debromination of alkyl bromide. The enhanced selectivity of NMP-ethylene glycol solvent mixture for aromatic hydrocarbon extraction has been analyzed by gas chromatography.

픽토그램

Health hazardExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

195.8 °F - Pensky-Martens closed cup

Flash Point (°C)

91 °C - Pensky-Martens closed cup


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Lot/Batch Number

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문서 라이브러리 방문

Evaluation of extraction properties of N-methylpyrrolidone and ethylene glycol mixtures by gas chromatography.
Wardencki W and Tameesh AHH.
Journal of Chemical Technology and Biotechnology, 31(1), 86-92 (1981)
NaBH4 in N-methylpyrrolidone: a safe alternative for hydride displacement reaction.
Torisawa Y, et al.
Bioorganic & Medicinal Chemistry Letters, 11(20), 2787-2789 (2001)
Aggregation of fullerene C60 in N-methylpyrrolidone.
Yevlampieva NP, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 209(2), 167-171 (2002)
N-methylpyrrolidone instead of phenol in treatment of lube feedstock.
Ivanov AV, et al.
Chemistry and Technology of Fuels and Oils, 36(5), 352-354 (2000)
Sanjairaj Vijayavenkataraman et al.
Artificial organs, 43(5), 515-523 (2018-09-20)
The incidence of peripheral nerve injuries is on the rise and the current gold standard for treatment of such injuries is nerve autografting. Given the severe limitations of nerve autografts which include donor site morbidity and limited supply, neural guide

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