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Merck
모든 사진(1)

주요 문서

53370

Sigma-Aldrich

L-Histidine monohydrochloride monohydrate

≥99.0% (AT)

동의어(들):

L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride

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About This Item

실험식(Hill 표기법):
C6H9N3O2 · HCl · H2O
CAS Number:
Molecular Weight:
209.63
Beilstein:
4168261
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥99.0% (AT)

양식

solid

광학 활성

[α]20/D +9.5±0.5°, c = 5% in 5 M HCl

불순물

≤0.3% foreign amino acids

mp

254 °C (dec.) (lit.)

solubility

H2O: 1 g/10 mL, clear, colorless (hot)

음이온 미량물

sulfate (SO42-): ≤100 mg/kg

양이온 미량물

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
NH4+: ≤500 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

InChI key

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

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일반 설명

L-Histidine is a hydrophilic essential amino acid that has a basic sidechain containing an imidazole group.

생화학적/생리학적 작용

L-Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. This essential amino acid can be degraded to glutamate by histidiase, urocanase and imidazolonepropionase; it is also the precursor of histamine by action of histidine decarboxylase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Biochemistry, 3rd. ed. (New York, NY)
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Biochemistry (3rd Edition), 19-20 (1988)
Textbook of Biochemistry with Clinical Correlations, 5th ed. (New York, NY)
Devlin, T. M., ed., Wiley-Liss
Biochemistry (5th Edition), 97-97 (2002)
Sean E Lehman et al.
Journal of pharmaceutical sciences, 110(5), 1948-1957 (2021-01-17)
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Neurochemistry international, 85-86, 31-39 (2015-05-06)
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