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Merck
모든 사진(1)

주요 문서

74680

Sigma-Aldrich

Octaethylene glycol monododecyl ether

BioXtra, ≥98.0% (GC)

동의어(들):

C12E8, Dodecyl octaethylene glycol ether, Dodecyloctaglycol, Polyoxyethylene (8) lauryl ether

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)8OH
CAS Number:
Molecular Weight:
538.75
Beilstein:
1893466
MDL number:
UNSPSC 코드:
12161900
PubChem Substance ID:
NACRES:
NA.25

설명

non-ionic

Quality Level

제품 라인

BioXtra

분석

≥98.0% (GC)

형태

solid

분자량

538.75 g/mol

CMC

0.11

양이온 미량물

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3

InChI key

YYELLDKEOUKVIQ-UHFFFAOYSA-N

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일반 설명

Octaethylene glycol monododecyl ether is a nonionic detergent.

애플리케이션

Detergent used for the study of membrane proteins in a native-like state, e.g. ATPase. Used in a mixed micellar assay for lipoxygenase acting at neutral pH and for functional reconstitution of influenza virus envelopes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Hiren Patel et al.
Biophysical chemistry, 150(1-3), 119-128 (2010-04-27)
We have studied the effect of two cosolvents, urea and glycerol, on the association and interactions of a surfactant, octaethyleneglycol dodecyl ether (C(12)EO(8)) and a phospholipid (POPC). We have measured the CMC, the partition coefficient, the effective mole fractions X(e)(sat)
M R Wenk et al.
Biophysical journal, 72(4), 1719-1731 (1997-04-01)
The interaction of the nonionic detergent octyl-beta-D-glucopyranoside (OG) with lipid bilayers was studied with high-sensitivity isothermal titration calorimetry (ITC) and solid-state 2H-NMR spectroscopy. The transfer of OG from the aqueous phase to lipid bilayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) can be
[Relationship between activity and tetraprotomeric structure of ion-transporting ATPases].
Kazuhiro Abe et al.
Seikagaku. The Journal of Japanese Biochemical Society, 79(6), 527-534 (2007-08-01)
Cédric Montigny et al.
Biochemical and biophysical research communications, 391(1), 1067-1069 (2009-12-17)
Many membrane proteins become labile when they are solubilized by detergent. Here we show that the presence of high concentrations of glycyl betaine stabilizes one of these proteins, the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1a), solubilized with nonionic detergents like n-dodecyl beta-d-maltopyranoside
M Bobrowska-Hägerstrand et al.
Biophysical journal, 77(6), 3356-3362 (1999-12-10)
Endovesicles induced in human erythrocytes by octaethyleneglycol dodecylether (C12E8) were studied by confocal laser scanning microscopy, using fluorescein isothiocyanate dextran as a nonspecific fluid marker. The endovesicles appeared to consist mainly of a ring-formed toroidal part joined with a central

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