91228

Trichloroacetic acid

BioUltra, ≥99.5% (T)

• 동의어(들): TCA
• Linear Formula: Cl₃CCOOH
• CAS Number: 76-03-9
• Molecular Weight: 163.39
• Beilstein: 970119
• EC Number: 200-927-2
• MDL number: MFCD00004177
• UNSPSC 코드: 12352101
• PubChem Substance ID: 57653428
• NACRES: NA.25

속성

• vapor density: <1 (vs air)
• vapor pressure: 1 mmHg ( 51 °C)
• 제품 라인: BioUltra
• 분석: ≥99.5% (T)
• 형태: crystals; flakes
• 불순물: insoluble matter, passes filter test
• 무기 잔류물: ≤0.05%
• refractive index: n20/D 1.62 (lit.)
• pH: <1.0 (25 °C, 0.5 M in H₂O)
• bp: 196 °C (lit.)
• mp: 54-58 °C (lit.)
• solubility: H₂O: 0.5 M at 20 °C, clear, colorless
• density: 1.62 g/mL at 25 °C (lit.)
• 음이온 미량물: chloride (Cl^-): ≤30 mg/kg; nitrate (NO₃^-): ≤20 mg/kg; phosphate (PO₄^3-): ≤10 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• 양이온 미량물: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: OC(=O)C(Cl)(Cl)Cl
• λ: 0.5 M in H₂O
• UV 흡수: λ: 260 nm A_max: 1.60; λ: 280 nm A_max: 0.15
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: YNJBWRMUSHSURL-UHFFFAOYSA-N

설명

일반 설명

Trichloroacetic acid (TCA) is derived from Trichloroethylene (TCE) metabolism. It is used as an acid decalcifying agent. TCA is used as a fixative for nuclear staining and protein precipitation.

애플리케이션

Trichloroacetic acid (TCA) has been used:

• to determine its effect on avian embryos during an exposure window encompassing cardiac specification
• as a cell fixative
• to terminate the O-acetylserine (thiol)lyase (OASTL) enzymatic assay
• for the precipitation of acidic ribosomal proteins (RPs)

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

기타 정보

Concentration of protein by quantitative precipitation; Cytochemical demonstration of DNA with a thiazine dye

안전성 정보

• 픽토그램: GHS05,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H314,H410
• 예방조치 성명서: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• Storage Class Code: 8B - Non-combustible corrosive hazardous materials
• WGK: WGK 2
• Flash Point (°F): >235.4 °F - closed cup
• Flash Point (°C): > 113 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges