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Merck
모든 사진(1)

주요 문서

T8637

Sigma-Aldrich

Thiamine monophosphate chloride dihydrate

동의어(들):

Aneurine monophosphate chloride

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About This Item

실험식(Hill 표기법):
C12H18ClN4O4PS · 2H2O
CAS Number:
Molecular Weight:
416.82
Beilstein:
3844977
EC Number:
MDL number:
UNSPSC 코드:
12352107
PubChem Substance ID:
NACRES:
NA.79

생물학적 소스

synthetic

Quality Level

분석

≥99.0% (HPLC)

양식

powder

기술

HPLC: suitable

색상

white to off-white

mp

190 °C

저장 온도

2-8°C

SMILES string

[Cl-].Cc1ncc(C[n+]2csc(CCOP(O)(O)=O)c2C)c(N)n1

InChI

1S/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H

InChI key

GUGWNSHJDUEHNJ-UHFFFAOYSA-N

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애플리케이션

Thiamine monophosphate chloride dihydrate has been used as a standard in high-performance liquid chromatography (HPLC) to quantify thiamine in plant exudates and to evaluate its purity.

생화학적/생리학적 작용

Thiamine monophosphate (TMP) is used as a substrate of thiamine-phosphate kinase (EC 2.7.4.16) and a precursor of thiamine pyrophosphate (TPP). TPP is a coenzyme involved in the catabolism of sugars and amino acids.
Thiamine monophosphate (TMP) is used as a substrate of thiamine-phosphate kinase (EC 2.7.4.16) and a precursor of thiamine pyrophosphate (TPP). TPP is a coenzyme involved in the catabolism of sugars and amino acids. TMP acts as an intermediate in the hydrolysis of thiamine pyrophosphate to thiamine.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Aminoff's Neurology and General Medicine, 47(12) (2014)
Purity of standard solutions of thiamine and its phosphate esters for HPLC analysis
Ihara H, et al.
Journal of Analytical Bio-Science, 25(3) (2002)
Structural studies of thiamin monophosphate kinase in complex with substrates and products
McCulloch KM, et al.
Biochemistry, 47(12), 3810-3821 (2008)
Maria Rapala-Kozik et al.
Plant physiology and biochemistry : PPB, 47(4), 237-242 (2009-01-27)
The pool of thiamine diphosphate (TDP), available for TDP-dependent enzymes involved in the major carbohydrate metabolic pathways, is controlled by two enzyme systems that act in the opposite directions. The thiamine pyrophosphokinase (TPK) activates thiamine into TDP and the numerous
Carsten Wrenger et al.
Biological chemistry, 387(1), 41-51 (2006-02-25)
Vitamin B1 (thiamine) is an essential cofactor for several key enzymes of carbohydrate metabolism. Mammals have to salvage this crucial nutrient from their diet to complement their deficiency of de novo synthesis. In contrast, bacteria, fungi, plants and, as reported

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