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Merck
모든 사진(1)

문서

A0433

Sigma-Aldrich

Anti-Albumin antibody produced in rabbit

IgG fraction of antiserum

동의어(들):

Anti Albumin Antibody

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

rabbit

결합

unconjugated

항체 형태

IgG fraction of antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

분자량

antigen 65 kDa

종 반응성

human

기술

indirect ELISA: 1:25,000
quantitative precipitin assay: 4.0-6.0 mg/mL

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... ALB(213)

일반 설명

Albumin is the most abundant plasma protein in humans.
Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin.

특이성

Rabbit polyclonal anti-Albumin antibody reacts with human serum and human albumin.

면역원

purified human albumin

애플리케이션

Anti-Albumin antibody produced in rabbit has been used in:
  • immunocytochemistry
  • immunoassay of amino-terminal fragments(ATF)-human serum albumin (HSA)
  • canstatin (Can) - human serum albumin (HSA)
  • enzyme-linked immunosorbent assay (ELISA)

생화학적/생리학적 작용

Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease. High levels of albumin are associated with dehydration. Albumin turnover is seen in infants with iron deficiency anemia. Advanced liver disease is associated with oxidative damage of albumin.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Shahid S Siddiqui et al.
American journal of physiology. Lung cellular and molecular physiology, 286(5), L1016-L1026 (2004-01-20)
Vascular endothelial cells undergo albumin endocytosis using a set of albumin binding proteins. This process is important for maintaining cellular homeostasis. We showed by several criteria that the previously described 73-kDa endothelial cell surface albumin binding protein is the 75-kDa
F Apparailly et al.
Gene therapy, 9(3), 192-200 (2002-02-23)
Plasmin is essential for metalloproteases activation, endothelial cell migration and degradation of the extracellular matrix. The process is common to neoangiogenesis pannus formation and cartilage degradation within arthritic joints. Since 80% of synovial cells express urokinase plasminogen activator receptor (uPAR)
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed
McLean AB, et al.
Stem Cells, 25(1), 29-38 (2007)
Canstatin gene electrotransfer combined with radiotherapy: preclinical trials for cancer treatment
Magnon C, et al.
Gene Therapy, 15(21), 1436-1436 (2008)
A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer
Frau E, et al.
Cancer Gene Therapy, 14(3), 251-251 (2007)

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