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Merck
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주요 문서

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A1394

Sigma-Aldrich

4-Aminophenyl α-D-mannopyranoside

≥98% (TLC)

동의어(들):

p-aminophenyl alpha-D-mannoside

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C12H17NO6
CAS Number:
34213-86-0
Molecular Weight:
271.27
MDL number:
MFCD00067366
UNSPSC 코드:
12352201
PubChem Substance ID:
24890539
NACRES:
NA.25

Quality Level

200

분석

≥98% (TLC)

양식

powder

광학 활성

[α]/D 123.00 to 135.00°, c = 9.00-11.00 mg/mL in methanol

기술

thin layer chromatography (TLC): suitable

색상

white to yellow cast

solubility

H2O: soluble

저장 온도

2-8°C

SMILES string

Nc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1

InChI

1S/C12H17NO6/c13-6-1-3-7(4-2-6)18-12-11(17)10(16)9(15)8(5-14)19-12/h1-4,8-12,14-17H,5,13H2

InChI key

MIAKOEWBCMPCQR-UHFFFAOYSA-N

관련 카테고리

애플리케이션

4-Aminophenyl α-D-mannopyranoside is used to modify the surface of liposomes to increase uptake kinetics.

기타 정보

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
0000128181
0000082751
0000241321
0000241320
0000229245

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문서 라이브러리 방문

Sumio Chono et al.
Drug development and industrial pharmacy, 36(1), 102-107 (2009-08-07)
The effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages (AMs) was evaluated in vitro and in vivo. 4-Aminophenyl-α-D-mannopyranoside (Man) was used for surface-mannose modification, and mannosylated liposomes with various mannosylation rates (particle size: 1000 nm) were prepared.
Xue Ying et al.
Pharmacology, 87(1-2), 105-114 (2011-02-02)
To circumvent the problem of transporting anticancer drugs across the blood-brain barrier (BBB) to target brain tumors, we have previously developed dual-targeting daunorubicin liposomes modified with 4-aminophenyl-α-D-manno-pyranoside and transferrin molecules. The objective of the present study was to evaluate the
Xue Ying et al.
Journal of controlled release : official journal of the Controlled Release Society, 141(2), 183-192 (2009-10-06)
Chemotherapy for brain glioma has been of limited value due to the inability of transport of drug across the blood-brain barrier (BBB) and poor penetration of drug into the tumor. For overcoming these hurdles, the dual-targeting daunorubicin liposomes were developed
M Triggiani et al.
Journal of immunology (Baltimore, Md. : 1950), 164(9), 4908-4915 (2000-04-26)
Secretory phospholipases A2 (sPLA2s) are a group of extracellular enzymes that release fatty acids at the sn-2 position of phospholipids. Group IIA sPLA2 has been detected in inflammatory fluids, and its plasma level is increased in inflammatory diseases. To investigate
Sofie Tanghe et al.
Molecular reproduction and development, 67(2), 224-232 (2003-12-25)
Several steps in the process of mammalian fertilization are mediated by carbohydrates. This study investigated the role of the p-aminophenyl derivative of d-mannose (APMP) during bovine fertilization. Inseminating cumulus-oocyte complexes (COCs) in the presence of increasing APMP concentrations resulted in
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