A1774

Amikacin disulfate salt

potency: 674-786 μg per mg (as amikacin base)

• 동의어(들): (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide disulfate, Antibiotic BB-K8 sulfate
• 실험식(Hill 표기법): C₂₂H₄₃N₅O₁₃ · 2H₂SO₄
• CAS Number: 39831-55-5
• Molecular Weight: 781.76
• Beilstein: 6172633
• EC Number: 254-648-6
• MDL number: MFCD00167475
• UNSPSC 코드: 51281632
• PubChem Substance ID: 24890586
• NACRES: NA.85

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 형태: powder or crystals
• 효능: 674-786 μg per mg (as amikacin base)
• 색상: white to off-white
• 항생제 활성 스펙트럼: Gram-negative bacteria; mycobacteria
• 동작 모드: protein synthesis | interferes
• 저장 온도: 2-8°C
• SMILES string: OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
• InChI: 1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;;/m0../s1
• InChI key: FXKSEJFHKVNEFI-GCZBSULCSA-N

설명

일반 설명

Chemical structure: aminoglycoside

애플리케이션

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .

생화학적/생리학적 작용

Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317,H361fd
• 예방조치 성명서: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Hazard Classifications: Repr. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)