14400

Biotin

≥99.0% (T)

• 동의어(들): D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
• 실험식(Hill 표기법): C₁₀H₁₆N₂O₃S
• CAS Number: 58-85-5
• Molecular Weight: 244.31
• Beilstein: 86838
• EC Number: 200-399-3
• MDL number: MFCD00005541
• UNSPSC 코드: 12352201
• eCl@ss: 34058011
• PubChem Substance ID: 329750287
• NACRES: NA.21

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥99.0% (T)
• 양식: powder
• 광학 활성: [α]20/D +91±2°, c = 1% in 0.1 M NaOH
• 무기 잔류물: ≤0.1% (as SO₄)
• 손실: ≤0.5% loss on drying
• 색상: colorless to white
• mp: 229-234 °C; 231-233 °C (lit.)
• solubility: alcohol: soluble 80mg/100 ml at 25 °C; water: soluble 22mg/100 ml at 25 °C; 0.1 M NaOH: 10 mg/mL at 25 °C, clear, colorless; H₂O: very soluble; organic solvents: insoluble
• 양이온 미량물: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• 응용 분야: detection
• SMILES string: [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
• InChI key: YBJHBAHKTGYVGT-ZKWXMUAHSA-N

설명

일반 설명

Biotin is readily available in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.

애플리케이션

Biotin has been used for testing the functionality of the Avidin-displaying phages. The product has also been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

생화학적/생리학적 작용

Biotin acts as an important cofactor for carboxylase enzymes in various metabolic pathways. Biotin favors keratin synthesis and hence is used as a supplement for hair and nail growth. Deficiency of biotin shows several symptoms such as alopecia, conjunctivitis, seborrheic dermatitis, depression, lethargy, hypotonia and seizures.

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

기타 정보

Reviews; Avidin-Biotin technology;

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)