M2574

Meropenem trihydrate

≥98% (HPLC), powder, antibacterial agent

• 동의어(들): (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
• 실험식(Hill 표기법): C₁₇H₂₅N₃O₅S · 3H₂O
• CAS Number: 119478-56-7
• Molecular Weight: 437.51
• MDL number: MFCD08600005
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: Meropenem trihydrate, ≥98% (HPLC)
• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to off-white
• solubility: DMSO: ≥20 mg/mL
• 주관자: AstraZeneca
• 저장 온도: −20°C
• SMILES string: O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O
• InChI: 1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1
• InChI key: CTUAQTBUVLKNDJ-OBZXMJSBSA-N

설명

일반 설명

Meropenem trihydrate (MRP) belongs to the carbapenem group of compounds. It is susceptible to degradation at high temperature and humidity. It is soluble in methanol-water or acetone-water combinations. It is used as an antibacterial agent for treating meningitis and pneumonia.

애플리케이션

Meropenem trihydrate has been used in the

• antibiotic susceptibility testing of E coli isolates from harbor estuary sediment samples
• in the bacterial killing assay and for screening antibiotic resistance of cystic fibrosis patient′s sputum based Staphylococcus aureus transformed macrophages in phagocyte infection
• for screening Enterococcus faecalis from human bile

생화학적/생리학적 작용

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic.

특징 및 장점

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H317,H334
• 예방조치 성명서: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable