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Merck
모든 사진(1)

주요 문서

C7039

Sigma-Aldrich

Cefotaxime sodium salt

powder or crystals, suitable for plant cell culture, BioReagent

동의어(들):

Cefotaxim sodium salt

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C16H16N5NaO7S2
CAS Number:
Molecular Weight:
477.45
Beilstein:
5711411
EC Number:
MDL number:
UNSPSC 코드:
10171502
PubChem Substance ID:
NACRES:
NA.72

제품명

Cefotaxime sodium salt, suitable for plant cell culture, BioReagent, powder or crystals

제품 라인

BioReagent

Quality Level

양식

powder or crystals

기술

cell culture | plant: suitable

색상

off-white to pale yellow

solubility

H2O: 10% ( )

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

응용 분야

agriculture

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key

AZZMGZXNTDTSME-JUZDKLSSSA-M

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일반 설명

Chemical structure: ß-lactam

애플리케이션

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

생화학적/생리학적 작용

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.
Mode of Action: Inhibits bacterial cell wall synthesis.

기타 정보

Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Valeria Di Dato et al.
Scientific reports, 9(1), 9893-9893 (2019-07-11)
Diatoms are phytoplankton eukaryotic microalgae that are widely distributed in the world's oceans and are responsible for 20-25% of total carbon fixation on the planet. Using transcriptome sequencing here we show for the first time that the ubiquitous diatom Thalassiosira
Bacterial nanoscale cultures for phenotypic multiplexed antibiotic susceptibility testing
Weibull E, et al.
Journal of Clinical Microbiology, 52(9), 3310-3317 (2014)
Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use.
AA C, et al.
Drugs (1983)
Metabolic profiling identifies trehalose as an abundant and diurnally fluctuating metabolite in the microalga Ostreococcus tauri
Hirth M, et al.
Metabolomics, 13(9), 68-68 (2017)
Anthony Ayodeji Adegoke et al.
Antimicrobial resistance and infection control, 9(1), 46-46 (2020-03-14)
The World Health Organization (WHO) recently classified Enterobacteriaceae resistance to third-generation cephalosporin into the group of pathogens with critical criteria for future research. A study to assess the antibiogram and beta-lactamase genes among the cefotaxime resistant E. coli (CREc) from

프로토콜

Reference guide and preparation guide for antibiotic and antimycotic use in plant tissue culture.

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