추천 제품
생물학적 소스
synthetic
Quality Level
분석
≥99% (titration)
양식
powder
기술
cell culture | mammalian: suitable
색상
white
mp
207-209 °C (dec.) (lit.)
solubility
H2O: 50 mg/mL
SMILES string
NCCCCCC(O)=O
InChI
1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI key
SLXKOJJOQWFEFD-UHFFFAOYSA-N
유전자 정보
human ... PLAT(5327) , PLG(5340)
rat ... Ppm1a(24666)
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관련 카테고리
애플리케이션
EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
생화학적/생리학적 작용
EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carboxypeptidase, plasmin, and plasminogen activator.
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
404.6 - 408.2 °F
Flash Point (°C)
207 - 209 °C
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
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문서
Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
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