A2512

Albumin from chicken egg white

lyophilized powder, ≥98% (agarose gel electrophoresis)

• 동의어(들): Albumin from hen egg white, Ovalbumin
• CAS Number: 9006-59-1
• EC Number: 232-692-7
• MDL number: MFCD00130424
• UNSPSC 코드: 12352202
• eCl@ss: 42010201
• NACRES: NA.61

속성

• 생물학적 소스: chicken egg white
• 유형: Grade VI
• 분석: ≥98% (agarose gel electrophoresis)
• 형태: lyophilized powder
• 분자량: 44287 Da by calculation
• 정제법: chromatography
• 라벨링 범위: 4-20 mol mannose per mol ovalbumin protein
• 기술: bioconjugation: suitable
• solubility: H₂O: soluble 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• UniProt 수납 번호: P01012
• 저장 온도: 2-8°C
• 유전자 정보: chicken ... OVAL(396058)

설명

일반 설명

Chicken egg albumin is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated-glycoprotein. From the amino acid sequence, the peptide portion of the molecule consists of 385 residues and has a molecular weight of 42.7 kDa.

Ovalbumin makes 75% of the total egg white protein.

애플리케이션

Ovalbumin has been used:

• as a medium for cell incubation in EliCell assay for the detection of released cytokines from eosinophil
• to induce allergic inflammation and atopic dermatitis in experimental mice
• as a component in control mixture for validating tandem mass spectral analysis
• as a model protein antigen to evaluate the in vivo efficacy of a chitosan/interleukin (IL)-12 adjuvant system

A phosphorylated glycoprotein which is useful as a marker (~45 kDa) for protein electrophoresis. Has been used to produce an animal model of asthma.

생화학적/생리학적 작용

Albumin from chicken egg white serves as a natural adhesive.

Differential scanning calorimetry indicates that chicken egg albumin denatures at 84 °C. Ovalbumin can be used as a carrier protein to conjugate to synthetic peptides for use as an immunogen. It has the following amino acids: 20 Lys, 10 Tyr, 6 Cys, 14 Asp, and 33 Glu which make it suitable for conjugation.

물리적 형태

Essentially salt free

제조 메모

A further purification of A 5503 to reduce mannose content.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H334
• 예방조치 성명서: P261 - P284 - P304 + P340 + P312 - P501
• Hazard Classifications: Resp. Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)