A8052

Arg-Gly-Asp

≥97% (TLC)

• 동의어(들): L-arginyl-glycyl-L-aspartic acid
• 실험식(Hill 표기법): C₁₂H₂₂N₆O₆
• CAS Number: 99896-85-2
• Molecular Weight: 346.34
• MDL number: MFCD00057952
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24891310
• NACRES: NA.32

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥97% (TLC)
• 양식: powder
• 기술: cell culture | stem cell: suitable
• UniProt 수납 번호: P02751
• 저장 온도: −20°C
• SMILES string: N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1
• InChI key: IYMAXBFPHPZYIK-BQBZGAKWSA-N
• 유전자 정보: human ... FN1(2335)

설명

Amino Acid Sequence

Arg-Gly-Asp

일반 설명

Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.

애플리케이션

Arg-Gly-Asp has been used:

• to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogel
• in adhesion assay
• in inhibition assay to confirm the β1-integrin-dependency of cell adhesion
• in textile fabrication and RGD textile functionalization
• to engineer a population of human dermal fibroblasts with impaired migration
• to modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)
• in the cell culture of human mammary epithelial cells

생화학적/생리학적 작용

Primary sequence involved with the binding of proteins to cell surfaces

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

제조 메모

Tripeptide from the cell-attachment domain of fibronectin

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)