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Merck
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주요 문서

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B1434

Sigma-Aldrich

BMP7, human

>95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

동의어(들):

BMP-7, OP-1, Osteogenic protein 1

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모든 사진(1)

About This Item

MDL number:
MFCD03702812
UNSPSC 코드:
12352202
NACRES:
NA.32

product name

Bone Morphogenetic Protein 7 human, >95% (SDS-PAGE), recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

생물학적 소스

human

Quality Level

100

재조합

expressed in CHO cells

분석

>95% (SDS-PAGE)

형태

lyophilized powder

효능

0.2-0.6 μg/mL ED50

분자량

monomer calculated mol wt 15.7 kDa
 18-20 kDa by SDS-PAGE (reducing)
 30-40 kDa by SDS-PAGE (non-reducing)

포장

pkg of 10 μg

저장 조건

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

UniProt 수납 번호

P18075

저장 온도

−20°C

유전자 정보

human ... BMP7(655)

생화학적/생리학적 작용

Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

물리적 형태

Lyophilized from 50.0 μl of a 0.2 μm filtered solution in 35% acetonitrile, 0.1% TFA containing 50 μg bovine serum albumin per 1μg of cytokine.

분석 메모

The biological activity is measured by its ability to induce alkaline phosphatase production using mouse ATDC-5 chondrogenic cells.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

A H Reddi
Nature biotechnology, 16(3), 247-252 (1998-04-07)
Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It has formed the basis for the emerging discipline of tissue engineering, which uses principles of molecular developmental biology and morphogenesis gleaned through
Effat Karimi Ghahfarrokhi et al.
The archives of bone and joint surgery, 9(5), 585-597 (2021-10-26)
Healing of large segmental bone defects can be challenging for orthopedic surgeons. This research was conducted to provide further insight into the effects of BMP7 in combination with autograft and platelet fibrin glue (PFG) on bone regeneration by Masquelet technique
A J Celeste et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(24), 9843-9847 (1990-12-01)
Characterization of the polypeptides present in bone-inductive protein extracts from bovine bone has led to the cloning of seven regulatory molecules, six of which are distantly related to transforming growth factor beta. The three human bone morphogenetic proteins (BMPs) we
Yan Wang et al.
Experimental and molecular pathology, 98(3), 393-402 (2015-03-17)
This study presented the effect of bone morphogenic protein-7 (BMP-7) inhibiting epithelial-mesenchymal transition (EMT) in silicosis model. In vivo, Wistar rats were exposed to silica by intratracheal instillation. Seven days later rats were treated with BMP-7. Rats were sacrificed at
Endre Kristóf et al.
Scientific reports, 5, 12540-12540 (2015-07-28)
Laser-scanning cytometry is presented as a tool allowing population scale analysis of ex vivo human brown adipogenic differentiation. It combines texture analysis and detection of Ucp1 protein content in single brown adipocytes of mixed cell populations with gene expression pattern
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