추천 제품
제품명
Bone Morphogenetic Protein 2 human, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
생물학적 소스
human
Quality Level
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
양식
lyophilized powder
분자량
26 kDa
포장
pkg of 10 μg
저장 조건
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
기술
cell culture | mammalian: suitable
불순물
endotoxin, tested
색상
white
solubility
water: soluble 0.100 mL, clear, colorless
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... BMP2(650)
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생화학적/생리학적 작용
Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.
물리적 형태
Lyophilized from a 0.2 μm filtered buffered solution containing 0.5 mg bovine serum albumin.
분석 메모
The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Jiaxuan Chen et al.
Journal of tissue engineering and regenerative medicine, 10(1), 40-51 (2013-06-21)
1α,25-Dihydroxyvitamin D3 [1α,25(OH)2D3] and bone morphogenetic protein-2 (BMP2) are both used to stimulate osteoblastic differentiation. 1α,25(OH)2D3 regulates osteoblasts through classical steroid hormone receptor mechanisms and through rapid responses that are mediated by two receptors, the traditional vitamin D receptor (VDR)
Martine M L Deckers et al.
Endocrinology, 143(4), 1545-1553 (2002-03-19)
During bone formation and fracture healing there is a cross-talk between endothelial cells and osteoblasts. We previously showed that vascular endothelial growth factor A (VEGF-A) might be an important factor in this cross-talk, as osteoblast-like cells produce this angiogenic factor
M Kawabata et al.
Cytokine & growth factor reviews, 9(1), 49-61 (1998-08-28)
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which are members of the transforming growth factor-beta (TGF-beta) superfamily. Activities of BMPs are extracellularly regulated by BMP-binding proteins, Noggin and Chordin. BMPs bind to two different types of serine-threonine kinase receptors, type
Ernst B Hunziker et al.
Tissue engineering. Part A, 21(13-14), 2089-2098 (2015-04-22)
The articular cartilage layer of synovial joints is commonly lesioned by trauma or by a degenerative joint disease. Attempts to repair the damage frequently involve the performance of autologous chondrocyte implantation (ACI). Healthy cartilage must be first removed from the
Eun-Cheol Lee et al.
International journal of molecular sciences, 21(16) (2020-08-17)
The role of dental pulp stem cells (DPSCs) in dental tissue regeneration is gaining attention because DPSCs can differentiate into odontoblasts and other specialized cell types. Epigenetic modification has been found to play an important role in cell differentiation and
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