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Merck
모든 사진(1)

주요 문서

C0742

Sigma-Aldrich

CKI-7 dihydrochloride

≥98% (HPLC), solid, CK1 inhibitor

동의어(들):

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

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About This Item

실험식(Hill 표기법):
C11H12ClN3O2S · 2HCl
CAS Number:
Molecular Weight:
358.67
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

제품명

CKI-7 dihydrochloride, ≥98% (HPLC), solid

Quality Level

분석

≥98% (HPLC)

양식

solid

저장 조건

desiccated

색상

white to light tan

solubility

H2O: >5 mg/mL

저장 온도

−20°C

SMILES string

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI key

JUAVTXYOCISSSL-UHFFFAOYSA-N

생화학적/생리학적 작용

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

주의사항

Material is hygroscopic

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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