C9538

Coenzyme Q₁₀

≥98% (HPLC), powder, antioxidant

• 동의어(들): CoQ10, Q-10, Ubiquinone 50, Ubiquinone-10
• 실험식(Hill 표기법): C₅₉H₉₀O₄
• CAS Number: 303-98-0
• Molecular Weight: 863.34
• Beilstein: 1900141
• EC Number: 206-147-9
• MDL number: MFCD00042919
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24893170
• NACRES: NA.77

속성

• 제품명: Coenzyme Q₁₀, ≥98% (HPLC)
• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: yellow to dark orange
• mp: 49 °C
• 응용 분야: cell analysis
• 저장 온도: −20°C
• SMILES string: O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O
• InChI: 1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
• InChI key: ACTIUHUUMQJHFO-UPTCCGCDSA-N

설명

일반 설명

Coenzyme Q (CoQ), also known as ubiquinone, is a lipid-soluble antioxidant and is an essential component of the mitochondrial electron transport chain. The molecule contains a biologically active quinone with a benzoquinone ring and an isoprenoid sidechain. Q10 is synthesized in the cytoplasm and mitochondria () which generates ATP through aerobic cellular respiration. CoQ10 is required for the optimal functioning of the immune system and for cardiovascular health (). The ability to repress inflammatory gene expression exhibits its anti-inflammatory property ( ) Genetic failure or ageing results in CoQ10 deficiency, indicated by suppression of immune function. ()

애플리케이션

Coenzyme Q10 (CoQ10) has been used:

• as a bioactive compound to study its immune modulating properties in vitro
• as a standard for high-performance liquid chromatography
• to study its effect on exercised rat aorta
• in the cellular CoQ uptake assay

생화학적/생리학적 작용

Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)