C9749

CBiPES hydrochloride

≥98% (HPLC)

• 동의어(들): N-(4′-cyano[1,1′-biphenyl]-3-yl)-N-(3-pyridinylmethyl)-ethanesulfonamide hydrochloride
• 실험식(Hill 표기법): C₂₁H₁₉N₃O₂S · HCl
• CAS Number: 856702-40-4
• Molecular Weight: 413.92
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 저장 조건: desiccated
• 색상: off-white to light brown
• solubility: DMSO: >20 mg/mL
• 주관자: Eli Lilly
• 저장 온도: 2-8°C
• InChI: 1S/C21H19N3O2S.ClH/c1-2-27(25,26)24(16-18-5-4-12-23-15-18)21-7-3-6-20(13-21)19-10-8-17(14-22)9-11-19;/h3-13,15H,2,16H2,1H3;1H
• InChI key: QKUHSVQWWZBAKM-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In rat brain, CBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamide, different chemical class from other mGlu2R agonists in the Sigma catalog.

특징 및 장점

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable