F3917

Forskolin

For use in molecular biology applications

• 동의어(들): 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one, Coleonol, Colforsin
• 실험식(Hill 표기법): C₂₂H₃₄O₇
• CAS Number: 66575-29-9
• Molecular Weight: 410.50
• Beilstein: 1692716
• EC Number: 266-410-9
• MDL number: MFCD00082317
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24894799
• NACRES: NA.52

속성

• 생물학적 소스: Coleus forskohlii
• Quality Level: 200
• 설명: for activation of T cells
• 제품 라인: BioReagent
• 분석: ≥98% (HPLC)
• 양식: powder
• 분자량: 410.50 g/mol
• 색상: white to off-white
• solubility: ethanol: soluble
• 적합성: suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells
• 저장 온도: room temp
• SMILES string: CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
• InChI: 1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
• InChI key: OHCQJHSOBUTRHG-KGGHGJDLSA-N

설명

일반 설명

Forskolin is a cell permeable diterpenoid isolated from Coleus forskohlii.

생화학적/생리학적 작용

Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H312
• 예방조치 성명서: P280 - P302 + P352 + P312 - P362 + P364 - P501
• Hazard Classifications: Acute Tox. 4 Dermal
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves