추천 제품
생물학적 소스
human
Quality Level
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
형태
lyophilized powder
효능
<0.50 ng/mL
분자량
predicted mol wt 8 kDa
포장
pkg of 10 and 50 μg
저장 조건
avoid repeated freeze/thaw cycles
불순물
endotoxin, tested
색상
white
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... NRG1(3084)
생화학적/생리학적 작용
Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.
분석 메모
The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Wei Tan et al.
The Journal of biological chemistry, 282(33), 24343-24351 (2007-06-15)
Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. Recently, altered expression of a novel isoform (type IV) in the brain has
Neural grafts containing exosomes derived from Schwann cell-like cells promote peripheral nerve regeneration in rats.
Hu, et al.
Burns & trauma, 11, tkad013-tkad013 (2023)
Shuji Wakatsuki et al.
Genes to cells : devoted to molecular & cellular mechanisms, 19(1), 66-77 (2013-11-22)
After peripheral nerve injury, Schwann cells gain a migratory phenotype and remodel their extracellular matrix to provide a supportive environment for axonal regeneration. The soluble neuregulin-1 isoform, that is, glial growth factor (GGF), is expressed in regenerating axons of injured
A M Addington et al.
Molecular psychiatry, 12(2), 195-205 (2006-10-13)
Childhood-onset schizophrenia (COS), defined as onset of psychosis by the age of 12, is a rare and malignant form of the illness, which may have more salient genetic influence. Since the initial report of association between neuregulin 1 (NRG1) and
Paul J Harrison et al.
Biological psychiatry, 60(2), 132-140 (2006-01-31)
Neuregulin 1 (NRG1) is a leading schizophrenia susceptibility gene. The NRG1 locus on chromosome 8p shows linkage to the disorder, and genetic association has been found between schizophrenia and various non-coding polymorphisms and haplotypes, especially at the 5' end of
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