E2250

Ellagic acid

≥95% (HPLC), powder, from tree bark

• 동의어(들): 4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase
• 실험식(Hill 표기법): C₁₄H₆O₈
• CAS Number: 476-66-4
• Molecular Weight: 302.19
• Beilstein: 47549
• EC Number: 207-508-3
• MDL number: MFCD00006914
• UNSPSC 코드: 12352205
• PubChem Substance ID: 24894460
• NACRES: NA.77

속성

• 생물학적 소스: tree bark
• Quality Level: 200
• 분석: ≥95% (HPLC)
• 양식: powder
• 유통기한: 5 yr
• solubility: 1 M NaOH: 10 mg/mL
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
• InChI: 1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
• InChI key: AFSDNFLWKVMVRB-UHFFFAOYSA-N
• 유전자 정보: human ... CSK(1445) , DYRK1A(1859) , GSK3B(2932) , SRC(6714) ; rat ... Lyn(81515) , Syk(25155)

설명

일반 설명

Ellagic acid is a naturally occurring phenolic acid in many fruits and vegetables, as a secondary plant metabolite. It is commonly found in green tea, pomegranate, strawberries, blackberries, raspberries, and walnuts.

애플리케이션

Ellagic acid has been used:

• to study the metabolism of dietary phenolic acids by Lactobacillus plantarum CECT 748T
• as a potential substrate for the high production of Lactobacillus plantarum tannase
• as a standard in the study to examine the phenolic components and anti-oxidant activity of nettle
• to study the links between dietary ellagic acid and epigenetic modulation of adipogenesis

생화학적/생리학적 작용

Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.

Ellagic acid has been found to exhibit antioxidant activity by virtue of having an inhibitory effect on the oxidation of low-density lipoproteins. This makes them have a cardioprotective effect on humans. In addition, it shows anticarcinogenic, antifibrotic, antiplasmodial, apoptotic, and chemopreventive activities as well.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves