E7906

Esomeprazole magnesium hydrate

≥98% (HPLC)

• 동의어(들): (S)-Omeprazole magnesium hydrate, (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-Magnesium hydrate, Nexium hydrate
• 실험식(Hill 표기법): C₃₄H₃₆MgN₆O₆S₂ · xH₂O
• CAS Number: 668985-31-7
• Molecular Weight: 713.12 (anhydrous basis)
• MDL number: MFCD11226784
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329799074
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D -128 to -146°, c = 0.5 in methanol
• 색상: white to off-white
• solubility: DMSO: ≥5 mg/mL
• 주관자: AstraZeneca
• 저장 온도: 2-8°C
• SMILES string: O.COc1ccc2n([Mg]n3c(nc4cc(OC)ccc34)S(=O)Cc5ncc(C)c(OC)c5C)c(nc2c1)S(=O)Cc6ncc(C)c(OC)c6C
• InChI: 1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;/t2*24-;;/m00../s1
• InChI key: LGRFYKXKCZKDLS-DIYDTZFBSA-N

설명

일반 설명

Esomeprazole is the (S)-isomer of omeprazole. It blocks the H⁺/K⁺-ATPase enzyme and lowers the release of hydrochloric acid by gastric parietal cells. Esomeprazole is used for treating gastroesophageal reflux disease (GERD).

애플리케이션

Esomeprazole magnesium hydrate has been used to induce intracellular acidification in an ATP12A-independent manner.

생화학적/생리학적 작용

Esomeprazole magnesium dihydrate is a leading proton pump inhibitor.

특징 및 장점

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)