추천 제품
product name
5-Fluoro-DL-tryptophan, powder or crystals
분석
≥95% (HPLC)
Quality Level
형태
powder or crystals
색상
slightly off-white to brown
응용 분야
detection
peptide synthesis
저장 온도
2-8°C
SMILES string
NC(Cc1c[nH]c2ccc(F)cc12)C(O)=O
InChI
1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)
InChI key
INPQIVHQSQUEAJ-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
- Determination of the 19F NMR chemical shielding tensor and crystal structure of 5-fluoro-dl-tryptophan.: This study provides a detailed analysis of the 19F NMR chemical shielding tensor and the crystal structure of 5-Fluoro-dl-tryptophan, offering valuable insights into its electronic environment and molecular interactions. Such detailed structural characterization is crucial for the development of fluorinated drugs and biomolecules, enhancing our understanding of their interactions and functionalities (Sykes BD et al., 2007).
생화학적/생리학적 작용
5-Fluoro-DL-tryptophan (5-F-TRP), a fluorine-containing analogue of tryptophan, may be incorporated into proteins such as cyclic AMP receptor protein (CRP) from Escherichia coli to study changes in ligand binding. 5-F-TRP may be used as an internal reference for chromatographic analysis of tryptophan and its derivatives found in whole blood.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
H Kinoshita et al.
Journal of bioscience and bioengineering, 92(6), 556-559 (2005-10-20)
In our study on nutritional requirement for the hyphal growth of Schizophyllum commune, we found that a Trp- mutant could not grow in the L-Trp-supplied medium in the presence of L-Ser. Further growth studies showed that not only L-Ser but
F Sixl et al.
The Biochemical journal, 266(2), 545-552 (1990-03-01)
Two fluorine-containing analogues of the cyclic AMP receptor protein (CRP) from Escherichia coli were prepared by biosynthetic incorporation of 5-fluorotryptophan (5-F-Trp) and 3-fluorotyrosine (3-F-Tyr). The 19F-n.m.r. spectrum of the [5-F-Trp]CRP showed two signals corresponding to the two tryptophan residues, and
N Aymard et al.
Progress in neuro-psychopharmacology & biological psychiatry, 18(1), 77-86 (1994-01-01)
1. 5-Hydroxytryptamine (5-HT) is a well known neurotransmitter implicated in mental disorders, tryptophan (Trp) as amino acid precursor may be interesting. 2. A rapid and simple reversed-phase (mu Bondapac C18 as stationary phase) liquid chromatographic method with fluorimetric detection (excitation:
Kenji Hamase et al.
Journal of chromatography. A, 1106(1-2), 159-164 (2006-01-31)
A sensitive assay for D-amino-acid oxidase (DAO) activity in mammalian tissues has been established. D-Tryptophan (D-Trp) analogs were tested as substrates for DAO, and 5-fluoro-D-tryptophan (D-FTP) was found to be the best substrate. By the enzymatic reaction, D-FTP was converted
S Rozovsky et al.
Journal of molecular biology, 310(1), 271-280 (2001-06-23)
Product release is partially rate determining in the isomerization reaction catalyzed by Triosephosphate Isomerase, the conversion of dihydroxyacetone phosphate to D-glyceraldehyde 3-phosphate, probably because an active-site loop movement is necessary to free the product from confinement in the active-site. The
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