추천 제품
생물학적 소스
human spleen
Quality Level
무균
sterile-filtered
유형
Type V
형태
liquid
포장
vial of 2 μg
농도
10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide
저장 온도
2-8°C
유전자 정보
human ... FTH1(2495) , FTL(2512)
애플리케이션
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
생화학적/생리학적 작용
A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Edward Pelle et al.
Journal of cosmetic science, 64(3), 175-179 (2013-06-12)
Menstruation and desquamation are important routes for humans to excrete iron. Because menstruation is no longer available in postmenopausal women, in the present study, we examined whether iron accumulates more in postmenopausal skin than in premenopausal skin. Skin biopsy samples
Samir Awadallah et al.
Clinical laboratory, 59(5-6), 687-691 (2013-07-20)
Total antioxidant capacity (TAC) and ischemia modified albumin (IMA) are common parameters used to assess the status of oxidative stress under different conditions. This study reports on TAC and levels of IMA in patients with beta-thalassemia major. Blood specimens were
Alex Brito et al.
Food and nutrition bulletin, 34(1), 14-20 (2013-06-19)
The Chilean Ministry of Health has combated iron deficiency through the delivery of fortified milk by the National Complementary Feeding Program (NCFP). To assess iron status and associations between biomarkers of iron status and serum C-reactive protein (CRP) in 218
Sebastien Leidgens et al.
The Journal of biological chemistry, 288(24), 17791-17802 (2013-05-04)
The mechanisms through which iron-dependent enzymes receive their metal cofactors are largely unknown. Poly r(C)-binding protein 1 (PCBP1) is an iron chaperone for ferritin; both PCBP1 and its paralog PCBP2 are required for iron delivery to the prolyl hydroxylase that
Rune J Ulvik et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 133(8), 845-849 (2013-04-25)
A low supply of iron in the diet may result in iron deficiency and mild iron-deficiency anaemia in healthy individuals. Women are more susceptible than men because of menstrual iron loss. We compared the effect of a low dose of
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