추천 제품
Quality Level
분석
≥99% (TLC)
mp
298-300 °C (dec.) (lit.)
항생제 활성 스펙트럼
fungi
동작 모드
DNA synthesis | interferes
protein synthesis | interferes
저장 온도
2-8°C
SMILES string
NC1=NC(=O)NC=C1F
InChI
1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
InChI key
XRECTZIEBJDKEO-UHFFFAOYSA-N
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일반 설명
Chemical structure: nucleoside
애플리케이션
Used in studies on TMP biosynthesis.
생화학적/생리학적 작용
Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
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In our previous works, we demonstrated that human neural stem cells (NSCs) transduced with the cytosine deaminase (CD) gene showed remarkable 'bystander killer effect' on glioma and medulloblastoma cells after administration of the prodrug 5-fluorocytosine (5-FC). In addition, herpes simplex
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