G1639

D-(+)-Galactosamine hydrochloride

BioReagent, suitable for cell culture

• 동의어(들): 2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride
• 실험식(Hill 표기법): C₆H₁₃NO₅ · HCl
• CAS Number: 1772-03-8
• Molecular Weight: 215.63
• Beilstein: 3697825
• EC Number: 217-198-1
• MDL number: MFCD00135830
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24895072
• NACRES: NA.75

속성

• 생물학적 소스: fish cartilage (shark)
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥99%
• 기술: cell culture | mammalian: suitable
• 불순물: Glucosamine, essentially free
• solubility: water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO
• InChI: 1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1
• InChI key: CBOJBBMQJBVCMW-NQZVPSPJSA-N

설명

애플리케이션

D-(+)-Galactosamine hydrochloride has been used to:

• induce livery injury
• inflammatory liver injury
• acute liver failure (ALF) in mice

생화학적/생리학적 작용

Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)