추천 제품
product name
Granulocyte-Macrophage Colony-Stimulating Factor human, GM-CSF, recombinant, expressed in E. coli, suitable for cell culture
생물학적 소스
human
Quality Level
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
형태
lyophilized powder
효능
≤0.1 ng/mL EC50
분자량
14.6 kDa
포장
pkg of 4X5 μg
pkg of 5 μg
저장 조건
avoid repeated freeze/thaw cycles
기술
cell culture | mammalian: suitable
불순물
≤1.000 EU/μg
색상
white
solubility
water: soluble 0.010 mL, clear, colorless
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... CSF2(1437) , CSF2(1437)
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일반 설명
Package size based on protein content
생화학적/생리학적 작용
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth and differentiation factor for cells in the granulocyte, macrophage and eosinophil lineage. GM-CSF stimulates colony formation from pluripotential progenitor cells at extremely low concentrations and is an essential survival and proliferative factor for hematopoietic progenitor cells in all divisions up to maturity. It also stimulates growth in some epithelial cells and osteoclasts. GM-CSF is produced by a variety of cell types (monocytes, endothelial cells, T-cells, fibroblasts, mitogen-stimulated B-cells, and LPS-stimulated macrophages). GM-CSF is secreted as a single chain glycoprotein containing 128 amino acids for human with a conserved disulfide bond. Human and murine GM-CSF share approx. 54% sequence homology and do not cross-react in bioactivity.
물리적 형태
Lyophilized from a 0.2 μm filtered, 10 mM sodium citrate, pH 3.5 solution.
분석 메모
The proliferative activity of human GM-CSF is tested in culture using human TF-1 cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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문서
Read article on hematopoietic cytokines and hematopoiesis
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