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Merck
모든 사진(2)

주요 문서

M6518

Sigma-Aldrich

Macrophage Colony-Stimulating Factor human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

동의어(들):

MCSF

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About This Item

MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.77

제품명

Macrophage Colony-Stimulating Factor human, M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

생물학적 소스

human

Quality Level

재조합

expressed in E. coli

분석

≥98% (SDS-PAGE and HPLC)

양식

lyophilized powder

효능

0.500-5.000 ng/mL ED50

품질

endotoxin tested

분자량

dimer 37 kDa

포장

pkg of 10 μg

기술

cell culture | mammalian: suitable

불순물

≤1.000 EU/μg

색상

white

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

human ... CSF1(1435)

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일반 설명

Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.

애플리케이션

Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.

생화학적/생리학적 작용

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

기타 정보

159 amino acids including N-terminal methionine (each monomer).

물리적 형태

Lyophilized from a sterile filtered buffered solution.

분석 메모

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서

Read article on hematopoietic cytokines and hematopoiesis

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