H108

Hemicholinium-3

solid, ≥95% (HPLC)

• 동의어(들): 2,2′-(4,4′-Biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium bromide)
• 실험식(Hill 표기법): C₂₄H₃₄Br₂N₂O₄
• CAS Number: 312-45-8
• Molecular Weight: 574.35
• Beilstein: 5704458
• EC Number: 206-227-3
• MDL number: MFCD00011978
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278169
• NACRES: NA.77

속성

• 분석: ≥95% (HPLC)
• 형태: solid
• 색상: white
• solubility: ethanol: 1.3 mg/mL; H₂O: 10 mg/mL
• SMILES string: [Br-].[Br-].C[N+]1(C)CCOC(O)(C1)c2ccc(cc2)-c3ccc(cc3)C4(O)C[N+](C)(C)CCO4
• InChI: 1S/C24H34N2O4.2BrH/c1-25(2)13-15-29-23(27,17-25)21-9-5-19(6-10-21)20-7-11-22(12-8-20)24(28)18-26(3,4)14-16-30-24;;/h5-12,27-28H,13-18H2,1-4H3;2*1H/q+2;;/p-2
• InChI key: OPYKHUMNFAMIBL-UHFFFAOYSA-L

설명

애플리케이션

Hemicholinium-3 has been used in the preparation of Krebs-HC-3 buffer to study its effects on choline uptake and choline acetyltransferase activity in differentiated human neuroblastoma (SK-N-SH) cells.

생화학적/생리학적 작용

Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain.

특징 및 장점

This compound is featured on the Acetylcholine Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331,H315,H319,H335
• 예방조치 성명서: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges