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Merck
모든 사진(5)

주요 문서

H1635

Sigma-Aldrich

N-Hippuryl-His-Leu hydrate

chromogenic, ≥98% (HPLC), powder

동의어(들):

N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate

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About This Item

실험식(Hill 표기법):
C21H27N5O5 · xH2O
CAS Number:
Molecular Weight:
429.47 (anhydrous basis)
Beilstein:
5664178
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32

제품명

N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC)

Quality Level

분석

≥98% (HPLC)

양식

powder

색상

white to off-white

solubility

acetic acid: ~50 mg/mL

저장 온도

−20°C

SMILES string

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1

InChI key

NWOJMNXIJBZMPK-QJHJCNPRSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

Amino Acid Sequence

NBz-Gly-His-Leu

애플리케이션

N-Hippuryl-His-Leu hydrate has been used in the measurement of angiotensin-converting enzyme (ACE) inhibitory activity using oyster hydrolysates, semimembranosus muscle samples, and rabbit lung acetone powder.

생화학적/생리학적 작용

N-Hippuryl-His-Leu hydrate (HHL) can be used as an artificial substrate for angiotensin-converting enzyme (ACE).

기질

Substrate for angiotensin converting enzyme.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
In Silico Elucidation of the Molecular Recognition of Phenol Derivative Compounds and Hippuryl-histidyl-leucine as an Artificial Substrate with the Experimental Target: Angiotensin-converting Enzyme
Vazquez-Valaldez VH, et al.
Letters in Drug Design & Discovery (2020)
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged
N Nahariah et al.
Asian-Australasian journal of animal sciences, 28(6), 855-861 (2015-02-27)
Lactobacillus plantarum is used for fermentation of fish products, meat and milk. However, the utilization of these bacteria in egg processing has not been done. This study was designed to evaluate the potential of fermented egg albumen as a functional
Flávia Giacometti Cavalheiro et al.
Food chemistry, 333, 127482-127482 (2020-07-14)
In order to evaluate differences in the peptide profile and bioactive potential in dairy products, by increasing the protein content and using proteolytic bacteria strain to enable the release of bioactive peptides, a high-protein yogurt with adjunct culture was developed.

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