추천 제품
생물학적 소스
human
Quality Level
재조합
expressed in HEK 293 cells
분석
>95% (SDS-PAGE)
형태
lyophilized powder
효능
≤0.6 ng/mL EC50
품질
endotoxin tested
분자량
dimer 14-19 kDa (glycosylated)
포장
pkg of 1 mg
pkg of 10 μg
pkg of 100 μg
제조업체/상표
HumanZyme
기술
cell culture | mammalian: suitable
불순물
<1 EU/μg
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
human ... IL4(3565)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Interleukin-4 (IL-4) is a pleiotropic cytokine and a complex glycoprotein mapped to human chromosome 5q31.1. It is produced by mast cells, basophils and a subset of activated T cells.
생화학적/생리학적 작용
Interleukin-4 (IL-4) interacts with interleukin 13 and is an interleukin-4 receptor ligand. It regulates IgE and IgG1 production by B cells. IL-4 favors glial and neuronal differentiation and regulates differentiation of naive cluster of differentiation CD4+ T cells to the T helper type 2 (TH2) cells. Polymorphism in the IL-4 gene is implicated in immune and inflammatory disorders. In cerebral infarction, IL-4 levels are elevated.
물리적 형태
Lyophilized from a 0.2 μm filtered solution of 1x PBS.
제조 메모
HumanKine Interleukin-4 (IL-4), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 14-19 kDa due to glycosylation, which is absent when this cytokine is expressed in E. coli. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
분석 메모
The activity is determined by the dose-dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
법적 정보
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Muscle as an endocrine organ
Muscle and Exercise Physiology, 13(4) (2019)
Interleukin 4 Receptor
Muscle and Exercise Physiology, 13(4) (1998)
IL-4: role in disease and regulation of production.
P Choi et al.
Clinical and experimental immunology, 113(3), 317-319 (1998-09-16)
Neurogenesis, Inflammation, and Mental Health
Inflammation and Immunity in Depression, 13(4) (2018)
Robert Y L Zee et al.
Human molecular genetics, 13(4), 389-396 (2003-12-19)
Candidate gene polymorphisms related to inflammation, thrombosis and lipid metabolism have been implicated in the development of ischemic stroke. Using DNA samples collected at baseline in a prospective cohort of 14 916 initially healthy American men, we genotyped 92 polymorphisms
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